Publications

Jacobs, A., Wei, C., Blumenthal, R. Understanding the Design Principles of Living Systems at the Nanoscale. Nanomedicine, in press.

Jacobs, A, Garg, H., Viard, M., Raviv, Y., Puri, A., Blumenthal, R. HIV-1 Envelope Glycoprotein-Mediated Fusion and Pathogenesis: Implications for Therapy and Vaccine Development, accepted for publication in Vaccine.

Jacobs, A., Quraishi, O., Francella, N., Bridon, D., Blumenthal, R. A covalent inhibitor targeting an intermediate conformation of the fusogenic subunit of the HIV-1 envelope complex. Manuscript accepted to J. Biol. Chem. August 28 (2007).

Sen, J., Jacobs, A., Jiang, H., Rong, L., Caffrey, M. The disulfide loop of gp41 is critical to the furin recognition site of HIV gp160. Protein Sci. 16 (6):1236-41 (2007).

Jacobs, A., Dimitrov, A.S., Finnegan, C.M.,Stiegler, G.,Katinger, H., Blumenthal, R. Exposure of the membrane-proximal external region of HIV-1 envelope glycoprotein-mediated fusion. Biochemistry. 280 (29):27284-8 (2005).

Jacobs, A., Simon, C., Caffrey, M. Thermostability of the HIV gp41 wild-type and loop mutations. Protein Pept. Lett. 13 (5): 477-80 (2006).

Jacobs A., Caffrey M. Alanine scanning mutants of the HIV gp41 loop. J. Biol. Chem. May 24 (2005).

Jacobs A., Hartman K, Laue T, Caffrey, M. Sedimentation velocity studies of the high-molecular weight aggregates of the HIV gp41 ectodomain. Protein Science. 13 (10): 2811-3 (2004).

Jiang S., Jacobs A., Laue T., Caffrey M. Solution structure of the coxsackievirus and adenovirus receptor domain 1. Biochemistry. 43 (7): 1847-53 (2004).

Gilhaudis L., Jacobs A., Caffrey M. Solution Structure of the HIV gp120 C5 Domain. Eur. J. Biochem. 269 (19): 4860-7 (2002).

Hakansson S., Jacobs A., Caffrey M. Heparin binding by the HIV-1 tat protein transduction domain. Protein Science. 10 (10): 2138-9 (2001).